TAGMe DNA Methylation Detection don Pan-cancer
Siffofin samfur
Magani mafi ƙanƙanta:Cire aƙalla 3mL Jini na jijiyoyi ko wasu nau'ikan samfurin asibiti masu dacewa
Daidaito:Ɗauki manyan bayanai da AI algorithm, gwada ƙayyadaddun ƙayyadaddun ≥95%
Yawanci:Gano ɗaya zai iya rufe manyan ciwace-ciwacen ƙwayar cuta guda 25.
Matakin farko:Sa baki daga gwajin farko na cutar kansa, a duk tsawon tsarin gano cutar kansa da jiyya.
dacewa:Ɗauki ƙa'idodin zinariya don gano methylation - fasahar jerin abubuwan pyrophosphate, na iya kammala gwajin cikin sa'o'i 4.
Hukuma:Tare da haƙƙin mallaka na ƙasa da ƙasa na 54, an buga sakamakon binciken da ya dace a cikin Binciken Ciwon daji, Binciken Genome da sauran shahararrun mujallu na duniya.
Ƙa'idar Ganewa
Ganewar cutar kansa gabaɗaya ita ce samfuran gwajin plasma ctDNA methylation waɗanda TAGMe suka haɓaka, wanda ke buƙatar aƙalla 3ml na duka jini don kamawa da tantance matsayin methylation na maki na musamman na ctDNA, don cimma farkon nunawa da ingantaccen sa ido. na kumburi.
Ayyuka
A cikin tabbatarwa fiye da samfuran asibiti na 3000, matakin methylation na TAGMe a cikin kyallen ƙwayar cuta ya fi girma fiye da na kyallen takarda na yau da kullun.Don haka, ana iya amfani da TAGMe azaman alamar ciwon daji don gano cututtukan daji daban-daban.
Kwayoyin da ke da alaƙa da Histone suna hypermethylated a cikin ciwon huhu na huhu da hypermethylated HIST1H4F na iya zama alamar cutar daji ta pan-cancer.
--- Binciken Ciwon daji, IDAN: 12.7
A matsayin alamar ciwon daji, TAGMe yana da ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙwayar cuta da hankali a cikin tabbatar da samfurin asibiti, wanda ke da ƙima mai mahimmanci don gano cutar sankarau.
Mahimmancin TAGMe a cikin samfuran ƙari daban-daban lokacin da ƙayyadaddun ya fi 95%,
Yanayin aikace-aikace
Tarihin iyali na ciwon daji:Masu ciwon daji a cikin dangi na kusa ko na jingina.
Kwayoyin cuta da cututtuka na kullum:Irin su HPV, HBV da sauran cututtuka na ƙwayoyin cuta, polyps na hanji, gastritis na kullum atrophic da hanta cirrhosis, da dai sauransu.
An fallasa ga yanayin cutar kansa na dogon lokaci:Bayyana ga yanayin radiation ko sinadarai masu haɗari na dogon lokaci.
Alamar ciwace da ake zargin:kamar zubar jinin al'ada ba bisa ka'ida ba, hematochezia, fitsari, nodules na huhu, rashin zazzaɓi ko rashin ƙarfi da ba a bayyana ba, da sauransu.
Rashin halayen rayuwa na dogon lokaci: Shan taba na dogon lokaci ko shan taba, yawan shan giya, cin abinci mai zafi ko sha mai zafi, cin gishiri mai yawa, tsintsin, m, kyafaffen abinci da soyayyen abinci, da sauransu.
Kula da yanayin lafiya:musamman ga kungiyar da ta haura shekaru 40
